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Professor Crowe is a Surgical Oncologist with a clinical and research interest in soft tissue sarcoma and breast cancer. He also practises endocrine surgery, including thyroid, parathyroid surgery and minimally invasive adrenal surgery. His clinical practice is at both POW public and private hospitals. He is Director of the Sydney Sarcoma Unit and co-director of the Sarcoma Research Group at UNSW, based on the Lowy Cancer Research Centre.